Number 1. (in 1 part) March 15, 2014
1. Mohamed S. Al-Braich, Nada K. Al-Husaini, Sama H. M. Saleh, Munira F. Awn
Effect of Adiponectin Level in Type II Diabetic Postmenopausal Women Compared to Healthy Women
European Journal of Medicine, 2014, Vol.(3), № 1, pp. 4-7
Number of views: 2795 Download in PDF
2. Imanali O. Baidaulet, Zulkiya I. Namazbaeva, Guljan N. Dossybayeva, Zhanbol B. Sabirov, Dinara S. KussainovaEuropean Journal of Medicine, 2014, Vol.(3), № 1, pp. 4-7
Abstract:
Adiponectin is protein secreted from adipose tissue and plays important role in regulating glucose level as well as fatty acid breakdown. Adipose tissue has been considered an important endocrine organ. Adiponectin has been shown to completely reverse insulin resistance. A total of sixty subjects involved in this study to examine the regulatory roles of adiponectin concentration in diabetic type II postmenopausal women and to study the correlation between the parameters (serum glucose, cholesterol and triglyceride). Thirty of each diabetic women (BMI<30) and healthy postmenopausal women (BMI<30) were selected from Baghdad teaching hospital in Baghdad/ Iraq. ELISA (enzyme linked immune sorbent assay) technique was used for the measurement of serum adiponectin. Blood glucose, cholesterol and triglyceride were determined by using colorimetric method. Results showed that the level of serum adiponectin in diabetic postmenopausal women were significantly (P < 0.01) lower than that of non diabetic postmenopausal women. Serum glucose in diabetic postmenopausal women was significantly (P < 0.01) higher than non-diabetic women. The present study indicates the possibility of future development of new anti-diabetic agents that act independent of insulin action.
Adiponectin is protein secreted from adipose tissue and plays important role in regulating glucose level as well as fatty acid breakdown. Adipose tissue has been considered an important endocrine organ. Adiponectin has been shown to completely reverse insulin resistance. A total of sixty subjects involved in this study to examine the regulatory roles of adiponectin concentration in diabetic type II postmenopausal women and to study the correlation between the parameters (serum glucose, cholesterol and triglyceride). Thirty of each diabetic women (BMI<30) and healthy postmenopausal women (BMI<30) were selected from Baghdad teaching hospital in Baghdad/ Iraq. ELISA (enzyme linked immune sorbent assay) technique was used for the measurement of serum adiponectin. Blood glucose, cholesterol and triglyceride were determined by using colorimetric method. Results showed that the level of serum adiponectin in diabetic postmenopausal women were significantly (P < 0.01) lower than that of non diabetic postmenopausal women. Serum glucose in diabetic postmenopausal women was significantly (P < 0.01) higher than non-diabetic women. The present study indicates the possibility of future development of new anti-diabetic agents that act independent of insulin action.
Number of views: 2795 Download in PDF
Estimation of Children Health Risk in Shymkent, Kazakhstan
European Journal of Medicine, 2014, Vol.(3), № 1, pp. 8-16
Number of views: 2684 Download in PDF
3. Natalia H. Horovenko, Svitlana V. Podolska, Zoryana R. KocherhaEuropean Journal of Medicine, 2014, Vol.(3), № 1, pp. 8-16
Abstract:
Negative environmental conditions of Shymkent increase the risk of lead accumulation in third generation of children, cause the problems with antioxidant protection of respiratory system, significantly reduce barrier-protective properties of cellular systems of tissue immunity, disturb hematopoiesis processes. Statistical data processing enabled us to determine the dependence of lead accretion in soil on the change in functional activity of cheek buccal cells, activity of catalase in expired breath condensate. Both the quantity of reticulocytes and the RPI change correction in accordance with the process of reticulocytes maturation during circulation in peripheral blood as early criterion of toxic anemia refer to haematological symptoms of lead intoxication.
Negative environmental conditions of Shymkent increase the risk of lead accumulation in third generation of children, cause the problems with antioxidant protection of respiratory system, significantly reduce barrier-protective properties of cellular systems of tissue immunity, disturb hematopoiesis processes. Statistical data processing enabled us to determine the dependence of lead accretion in soil on the change in functional activity of cheek buccal cells, activity of catalase in expired breath condensate. Both the quantity of reticulocytes and the RPI change correction in accordance with the process of reticulocytes maturation during circulation in peripheral blood as early criterion of toxic anemia refer to haematological symptoms of lead intoxication.
Number of views: 2684 Download in PDF
Peculiarities of Polymorphism in Glutathione S-transferase Genes in Newborns From Different Ecological Zones of Ivano-Frankivsk region
European Journal of Medicine, 2014, Vol.(3), № 1, pp. 17-28
Number of views: 2668 Download in PDF
4. Elena I. Sycheva, Antonina V. PolyakovaEuropean Journal of Medicine, 2014, Vol.(3), № 1, pp. 17-28
Abstract:
It has been established that the frequency of polymorphic variants of GSTM1 "+" genes was 43.70 % and the frequency of polymorphic variants of GSTM1 "-"genes made up 56.30 % correspondingly in all newborns in the region, without division into ecological zones. Speaking about GSTT1genes the frequencies of polymorphic variants of GSTТ1«+» and GSTТ1«-» were 80.67 % and 19.33 % correspondingly. Positive micro-nucleus test was found in none of the carriers of GSTТ1«-» polymorphic variant. GSTT1«+» allelic variant was found in all newborns with negative micro-nucleus test. 78.38 % predominance in associations of GSTM1«+»/GSTT1 genotypes is characteristic of newborns with negative micro-nucleus test. Our studies have shown the diagnostic value of molecular-genetic testing in conjunction with the micro-nucleus testing for predicting newborns’ genome sensitivity to total exposure of environmental factors.
It has been established that the frequency of polymorphic variants of GSTM1 "+" genes was 43.70 % and the frequency of polymorphic variants of GSTM1 "-"genes made up 56.30 % correspondingly in all newborns in the region, without division into ecological zones. Speaking about GSTT1genes the frequencies of polymorphic variants of GSTТ1«+» and GSTТ1«-» were 80.67 % and 19.33 % correspondingly. Positive micro-nucleus test was found in none of the carriers of GSTТ1«-» polymorphic variant. GSTT1«+» allelic variant was found in all newborns with negative micro-nucleus test. 78.38 % predominance in associations of GSTM1«+»/GSTT1 genotypes is characteristic of newborns with negative micro-nucleus test. Our studies have shown the diagnostic value of molecular-genetic testing in conjunction with the micro-nucleus testing for predicting newborns’ genome sensitivity to total exposure of environmental factors.
Number of views: 2668 Download in PDF
Syndrom-Pathogen Effect of Ozone Therapy and Nauheim Baths on Patients with Cardiovascular Disease
European Journal of Medicine, 2014, Vol.(3), № 1, pp. 29-42
Number of views: 2604 Download in PDF
5. Mikhail Yu. Vereshchagin, Aleksandr U. MinkinEuropean Journal of Medicine, 2014, Vol.(3), № 1, pp. 29-42
Abstract:
Despite different theories of atherogenesis, pathogenesis of this disease is, foremost, associated with the lipid storage disease, blood rheological properties, lipid peroxidation. Microcirculation disorders have significant role for pathogenesis of many illnesses, primarily, cardiovascular. Among possible reasons of increased risk of their pathway are the increase in the activity of sympathetic neurovegetative system, psychoemotional tension emergion. Application of ‘gas’ therapy methods, such as ozone therapy and carbon dioxide in the form of Nauheim baths is one of the prospect trends in preventive treatment. The obtained results of these methods application in the course of resort treatment showed positive dynamics for homeostasis indicants. They can serve as an indication for the use of carbon dioxide and, especially, ozone therapy for multifactor preventive treatment of patients with cardiovascular diseases.
Despite different theories of atherogenesis, pathogenesis of this disease is, foremost, associated with the lipid storage disease, blood rheological properties, lipid peroxidation. Microcirculation disorders have significant role for pathogenesis of many illnesses, primarily, cardiovascular. Among possible reasons of increased risk of their pathway are the increase in the activity of sympathetic neurovegetative system, psychoemotional tension emergion. Application of ‘gas’ therapy methods, such as ozone therapy and carbon dioxide in the form of Nauheim baths is one of the prospect trends in preventive treatment. The obtained results of these methods application in the course of resort treatment showed positive dynamics for homeostasis indicants. They can serve as an indication for the use of carbon dioxide and, especially, ozone therapy for multifactor preventive treatment of patients with cardiovascular diseases.
Number of views: 2604 Download in PDF
Role of Chronic Polypous Rhinosinusitis in Contraction of Cancer of Nasal Cavity and Paranasal Sinuses
European Journal of Medicine, 2014, Vol.(3), № 1, pp. 43-48
Number of views: 2714 Download in PDF
6. European Journal of Medicine, 2014, Vol.(3), № 1, pp. 43-48
Abstract:
There is a growing number of patients with malignant tumors of nasal cavity and paranasal sinuses. Majority of patients with this pathology are hospitalized with III-IV cancer stages. There is no tendency to decrease the advanced stage of cancer. The efficiency of patients’ treatment can be increased by early diagnostics. The main reason of delayed diagnostics is insufficient oncologic alarm in primary health care. While the background prodromic cancer processes are morphologically detected in 56.7 % of patients, the issues of treatment policy during cavity and paranasal sinuses premalignancy are still unsettled. Chronic polypous rhinosinusitis is one of the most frequent background process of cancer of nasal cavity and paranasal sinuses. Rhinosinusitis morbidity is high; the growth of its incidence is 2–4 % per year in the last decade. There are few works, considering polypous rhinosinusitis as premalignant condition.
There is a growing number of patients with malignant tumors of nasal cavity and paranasal sinuses. Majority of patients with this pathology are hospitalized with III-IV cancer stages. There is no tendency to decrease the advanced stage of cancer. The efficiency of patients’ treatment can be increased by early diagnostics. The main reason of delayed diagnostics is insufficient oncologic alarm in primary health care. While the background prodromic cancer processes are morphologically detected in 56.7 % of patients, the issues of treatment policy during cavity and paranasal sinuses premalignancy are still unsettled. Chronic polypous rhinosinusitis is one of the most frequent background process of cancer of nasal cavity and paranasal sinuses. Rhinosinusitis morbidity is high; the growth of its incidence is 2–4 % per year in the last decade. There are few works, considering polypous rhinosinusitis as premalignant condition.
Number of views: 2714 Download in PDF