Number 1. (in 1 part) June 20, 2014
1. Aleksandr N. Bitsadze
Possibilities of Application of the Method of Biological Feedback in Resort Treatment of Patients with Cerebrovascular Diseases
European Journal of Medicine, 2014, Vol.(4), № 2, pp. 52-56
Number of views: 2621 Download in PDF
2. Andrii N. BushtrukEuropean Journal of Medicine, 2014, Vol.(4), № 2, pp. 52-56
Abstract:
The article studies the possibilities of the application of the principle of biological rheoencephalogram feedback in rehabilitation of patients with cerebrovascular diseases in resort environment, detects positive dynamics of rheoencephalogram measures and the symptom index in the patients with vascular dyscirculatory encephalopathy with the use of functional biocontrol, which proves the clinical efficiency of the method of treatment and rehabilitation procedures, applied in the patients with cerebrovascular diseases.
The article studies the possibilities of the application of the principle of biological rheoencephalogram feedback in rehabilitation of patients with cerebrovascular diseases in resort environment, detects positive dynamics of rheoencephalogram measures and the symptom index in the patients with vascular dyscirculatory encephalopathy with the use of functional biocontrol, which proves the clinical efficiency of the method of treatment and rehabilitation procedures, applied in the patients with cerebrovascular diseases.
Number of views: 2621 Download in PDF
Growth and Microhardness of the Rat’s Tibia in Different Ages after Fracture Modeling
European Journal of Medicine, 2014, Vol.(4), № 2, pp. 57-64
Number of views: 2447 Download in PDF
3. Ekaterina A. Filippova, Alexander V. Korobeynikov, Denis V. LozhkarevEuropean Journal of Medicine, 2014, Vol.(4), № 2, pp. 57-64
Abstract:
Bone injury is a powerful factor that leads to remodeling of the entire organ. When this change rate adjustment processes dependent on many factors including the age. There is strong evidence of changes in the skeleton of a young, mature and old age in terms of long bone injuries. But it is poorly understood changes in other age periods. The aim of our work was to study bone growth and bone microhardness after defect modeling of the tibia in animals of different age periods. Under sterile operating was applied defect of medial surface of the body with the middle third of the tibia. After 10, 15 and 24 days after defect application were study osteometric parameters and bone microhardness. Tibia injury leads to disruption of the longitudinal growth processes in animals of young and adult ages, which is probably due to dysfunction of the epiphyseal growth plate. Also seen the development of periosteal reaction, which is accompanied by changes in the transverse dimensions of the bone. In animals of presenile and senile ages were not observe changes of bone growth parameters. Microhardness bone tends to lower in animals of all ages. While in rats of young and adult ages observed normalization of this parameter to the 24 day, in animals of presenile and senile age there is a decrease of microhardness, which is a risk factor for recurrent fractures.
Bone injury is a powerful factor that leads to remodeling of the entire organ. When this change rate adjustment processes dependent on many factors including the age. There is strong evidence of changes in the skeleton of a young, mature and old age in terms of long bone injuries. But it is poorly understood changes in other age periods. The aim of our work was to study bone growth and bone microhardness after defect modeling of the tibia in animals of different age periods. Under sterile operating was applied defect of medial surface of the body with the middle third of the tibia. After 10, 15 and 24 days after defect application were study osteometric parameters and bone microhardness. Tibia injury leads to disruption of the longitudinal growth processes in animals of young and adult ages, which is probably due to dysfunction of the epiphyseal growth plate. Also seen the development of periosteal reaction, which is accompanied by changes in the transverse dimensions of the bone. In animals of presenile and senile ages were not observe changes of bone growth parameters. Microhardness bone tends to lower in animals of all ages. While in rats of young and adult ages observed normalization of this parameter to the 24 day, in animals of presenile and senile age there is a decrease of microhardness, which is a risk factor for recurrent fractures.
Number of views: 2447 Download in PDF
Clustering of the Parameters of Rhythmographic Analysis of Man’s Electrocardiogram
European Journal of Medicine, 2014, Vol.(4), № 2, pp. 65-71
Number of views: 2598 Download in PDF
4. Oleh N. Mishenko, Ivan N. Babich, Natalia V. Zaytceva, Maxim V. PogorielovEuropean Journal of Medicine, 2014, Vol.(4), № 2, pp. 65-71
Abstract:
The article considers the clustering of the parameters of man’s heart rate variability. The technique of parameters calculation and diagrams of rhythmographic analysis construction are presented. The algorithm of conceptual clustering Cobweb, modified for quantitative data, is used for parameters clustering. The results of the experiments prove the efficiency of the division of the learning range of electrocardiograms into the groups similar in terms of rhythmographic parameters. The practical application of the offered method as a part of the software support of electrocardiograms analysis will enable to provide operational evaluation of the rhythmographic nature of heart function in the course of screening examinations or in the emergency medicine for diagnosing and prediction.
The article considers the clustering of the parameters of man’s heart rate variability. The technique of parameters calculation and diagrams of rhythmographic analysis construction are presented. The algorithm of conceptual clustering Cobweb, modified for quantitative data, is used for parameters clustering. The results of the experiments prove the efficiency of the division of the learning range of electrocardiograms into the groups similar in terms of rhythmographic parameters. The practical application of the offered method as a part of the software support of electrocardiograms analysis will enable to provide operational evaluation of the rhythmographic nature of heart function in the course of screening examinations or in the emergency medicine for diagnosing and prediction.
Number of views: 2598 Download in PDF
Morphological Estimation of Bone Tissue in Peri-implant Zone if Using Dental Implants of Different Composition
European Journal of Medicine, 2014, Vol.(4), № 2, pp. 72-86
Number of views: 2683 Download in PDF
5. Alexandr N. OleshkoEuropean Journal of Medicine, 2014, Vol.(4), № 2, pp. 72-86
Abstract:
Modern implantology has a wide range of materials, which have established reputation throughout decades. The mostly wide used material is titanium and its alloys, which have demonstrated satisfactory biological properties and the lack of corrosion. Though, there are data on the possible spontaneous fatigue fractures of jaw because of the disconformity of the mechanical properties of the implant and the bone tissue and the forming of the connective tissue along the material. This work compares the reaction of tissues to the implantation of different materials, both traditional (TiVT6, Ti-1, 3Si-20Nb, Ti-1, 9Si) and innovative, such as zirconium implants with hydroxylapatite coating with the use of microplasmous spraying. To evaluate the tissue reaction, stereoscanning microscopy with microanalysis was applied. It enables to evaluate both the morphology of peri-implant zone and detect the migration of implant elements into the surrounding tissues. The results of the research have showed the advantages of the innovative materials, which become apparent in their high osteo-integration properties, providing adherence of implant to alveolar socket. Traditional materials have showed the migration of titanium and silicon into the surrounding tissues and the possible toxic impact on the osteoblastic differentiation.
Modern implantology has a wide range of materials, which have established reputation throughout decades. The mostly wide used material is titanium and its alloys, which have demonstrated satisfactory biological properties and the lack of corrosion. Though, there are data on the possible spontaneous fatigue fractures of jaw because of the disconformity of the mechanical properties of the implant and the bone tissue and the forming of the connective tissue along the material. This work compares the reaction of tissues to the implantation of different materials, both traditional (TiVT6, Ti-1, 3Si-20Nb, Ti-1, 9Si) and innovative, such as zirconium implants with hydroxylapatite coating with the use of microplasmous spraying. To evaluate the tissue reaction, stereoscanning microscopy with microanalysis was applied. It enables to evaluate both the morphology of peri-implant zone and detect the migration of implant elements into the surrounding tissues. The results of the research have showed the advantages of the innovative materials, which become apparent in their high osteo-integration properties, providing adherence of implant to alveolar socket. Traditional materials have showed the migration of titanium and silicon into the surrounding tissues and the possible toxic impact on the osteoblastic differentiation.
Number of views: 2683 Download in PDF
Age Futures of Wound Treatment With Chitosan Films Application
European Journal of Medicine, 2014, Vol.(4), № 2, pp. 87-100
Number of views: 2432 Download in PDF
6. Shakhnoza E. Usmanova, Аbdujalol V. Yakubov, Аbror А. KhamraevEuropean Journal of Medicine, 2014, Vol.(4), № 2, pp. 87-100
Abstract:
Injuries are among the most frequent causes of hospitalization in emergency surgery clinics. Currently, the incidence of injuries in the population is 1:1000 per year, and the mortality rate ranges from 1.5 to 5.9 %. For treatment of wounds uses a wide range of the local application on the basis of natural and artificial ingredients. In recent decades, a number of studies devoted to the use of chitosan for the treatment of wounds of various etiologies. But data regarding the activities of chitosan-based materials on the treatment of wounds of mechanical etiology in age aspect are pure. The aim of our research – the study of the parameters of wound surface in animals of different ages during the application of chitosan membranes. The experiment was conducted on 180 laboratory animals – young, mature and old age, which simulated mechanical trauma in interscapullar area. Experimental series were carried out daily applique innovative chitosan membranes. To control the process of skin regeneration was used method of planimetric study. Age features of mechanical etiology wound healing are to reduce the speed of cleaning the surface of the necrotic mass and slowing the formation of the epithelial layer. Application of chitosan membranes for the treatment of mechanical trauma leads to an acceleration of cleansing the wound from necrotic tissue, increased the speed of transformation of granulation in the connective tissue and as a result – complete epithelialization of the defect without scar formation.
Injuries are among the most frequent causes of hospitalization in emergency surgery clinics. Currently, the incidence of injuries in the population is 1:1000 per year, and the mortality rate ranges from 1.5 to 5.9 %. For treatment of wounds uses a wide range of the local application on the basis of natural and artificial ingredients. In recent decades, a number of studies devoted to the use of chitosan for the treatment of wounds of various etiologies. But data regarding the activities of chitosan-based materials on the treatment of wounds of mechanical etiology in age aspect are pure. The aim of our research – the study of the parameters of wound surface in animals of different ages during the application of chitosan membranes. The experiment was conducted on 180 laboratory animals – young, mature and old age, which simulated mechanical trauma in interscapullar area. Experimental series were carried out daily applique innovative chitosan membranes. To control the process of skin regeneration was used method of planimetric study. Age features of mechanical etiology wound healing are to reduce the speed of cleaning the surface of the necrotic mass and slowing the formation of the epithelial layer. Application of chitosan membranes for the treatment of mechanical trauma leads to an acceleration of cleansing the wound from necrotic tissue, increased the speed of transformation of granulation in the connective tissue and as a result – complete epithelialization of the defect without scar formation.
Number of views: 2432 Download in PDF
Assessment of the Impact of Some Inhibitors of Angiotensin-converting Ferment, Omeprazole and Their Combinations on the Frequency of Erosive Ulcerous Disorders of Gastric Mucosa When Administered with Indometacin
European Journal of Medicine, 2014, Vol.(4), № 2, pp. 101-108
Number of views: 2979 Download in PDF
7. European Journal of Medicine, 2014, Vol.(4), № 2, pp. 101-108
Abstract:
The examination of 144 white mature male rats of mixed population was conducted. Experimental rheumatoid arthritis model was used to study the impact of some ACE inhibitors: omeprazole, cytotek and combinations of omeprazole with ACE inhibitors and cytotek on frequency of erosive ulcerous injuries of gastric mucosa when administered within 5 and 10 days with indometacin. Drugs were administered per os in the form of water suspension. It was established that the combined use of ACE inhibitors, omeprazole and cytotek with indometacin decreases the noci-influence of indometacin on gastric mucosa. Captopril is the most treatment medication among ACE inhibitors. Combined application of ACE inhibitors with omeprazole and cytotek increases the medicine efficacy. Com- bined use of omeprazole and captopril or omeprazole and cytotek is the most effective for prevention of side effect of indometacin on mucosa of gastroduodenal zone.
The examination of 144 white mature male rats of mixed population was conducted. Experimental rheumatoid arthritis model was used to study the impact of some ACE inhibitors: omeprazole, cytotek and combinations of omeprazole with ACE inhibitors and cytotek on frequency of erosive ulcerous injuries of gastric mucosa when administered within 5 and 10 days with indometacin. Drugs were administered per os in the form of water suspension. It was established that the combined use of ACE inhibitors, omeprazole and cytotek with indometacin decreases the noci-influence of indometacin on gastric mucosa. Captopril is the most treatment medication among ACE inhibitors. Combined application of ACE inhibitors with omeprazole and cytotek increases the medicine efficacy. Com- bined use of omeprazole and captopril or omeprazole and cytotek is the most effective for prevention of side effect of indometacin on mucosa of gastroduodenal zone.
Number of views: 2979 Download in PDF