Number 1. (in 1 part) September 07, 2013
1. Galina D. Bryukhanova, Andrey A. Schetkin
Current Problems of Food Safety in Terms of Russia Membership in World Trade Organization
European Journal of Medicine, 2013, Vol.(1), № 1, p. 4-10.
Number of views: 2820 Download in PDF
2. Anatolij T. Bykov, Kirill V. GordonEuropean Journal of Medicine, 2013, Vol.(1), № 1, p. 4-10.
Abstract:
Food industry stirs close interest of researches due to the extension and deepening of the problems of ecologic, microbiologic, epidemiologic safety of food industry and intake, determined by many social, anthropogenic and natural factors: change of human food ration; world economy globalization and, in particular, food market due to the penetration of pathogens, toxins into the new territories; adaptation of pathogenic agents to food storage conditions and new factors of transmission and other reasons. As a result, food-borne diseases significantly determine the increase of infectious and non-infectious pathologies in the world, including economically developed countries. The paper presents the data on the existing systems of catering risk control, current data on the role of some food pathogens in alimentary outbreaks, offers measures to increase food safety in the Russian Federation on both national and federal levels in terms of its membership in World Trade Organization.
Food industry stirs close interest of researches due to the extension and deepening of the problems of ecologic, microbiologic, epidemiologic safety of food industry and intake, determined by many social, anthropogenic and natural factors: change of human food ration; world economy globalization and, in particular, food market due to the penetration of pathogens, toxins into the new territories; adaptation of pathogenic agents to food storage conditions and new factors of transmission and other reasons. As a result, food-borne diseases significantly determine the increase of infectious and non-infectious pathologies in the world, including economically developed countries. The paper presents the data on the existing systems of catering risk control, current data on the role of some food pathogens in alimentary outbreaks, offers measures to increase food safety in the Russian Federation on both national and federal levels in terms of its membership in World Trade Organization.
Number of views: 2820 Download in PDF
Medical Cluster of Olympic Legacy: Prospects and Possibilities of Use
European Journal of Medicine, 2013, Vol.(1), № 1, p. 11-14.
Number of views: 2692 Download in PDF
3. Kirill V. Gordon, Eduard S. KhudoevEuropean Journal of Medicine, 2013, Vol.(1), № 1, p. 11-14.
Abstract:
Sochi is the main resort and recreation area on the Black Sea coast of Russia with coastal and mountain climates. Modernization of the city infrastructure and healthcare institutions, carried out due to Winter Olympic Games 2014 host, creates the unique environment for the realization of large-scale healthcare projects in the post-Games period. Current scientific and practical experience enable to start the program of medical, preventive and rehabilitation health services development, aimed at the improvement of population health. The positive example is the experience of rehabilitation of female athletes with reproductive function disorders.
Sochi is the main resort and recreation area on the Black Sea coast of Russia with coastal and mountain climates. Modernization of the city infrastructure and healthcare institutions, carried out due to Winter Olympic Games 2014 host, creates the unique environment for the realization of large-scale healthcare projects in the post-Games period. Current scientific and practical experience enable to start the program of medical, preventive and rehabilitation health services development, aimed at the improvement of population health. The positive example is the experience of rehabilitation of female athletes with reproductive function disorders.
Number of views: 2692 Download in PDF
Aspects of Medical and Psychological Rehabilitation of Patients after Aesthetic Breast Surgery
European Journal of Medicine, 2013, Vol.(1), № 1, p. 15-21.
Number of views: 2601 Download in PDF
4. Isaak Ya. Gurovich, Oleg O. PapsuevEuropean Journal of Medicine, 2013, Vol.(1), № 1, p. 15-21.
Abstract:
Breast prosthesis with aesthetic purposes is widespread throughout the world and has been rapidly spreading within Russia in recent years. Since the frequency of breast postoperative complications and repeated surgery does not tend to decrease, it is advisable to examine patients more thoroughly to choose the appropriate surgery. Postoperative medical rehabilitation is also required to improve the psycho-emotional state, prevent early and delayed postoperative complications and increase the quality of life of women. This technology can be successfully used in regenerative medicine.
Breast prosthesis with aesthetic purposes is widespread throughout the world and has been rapidly spreading within Russia in recent years. Since the frequency of breast postoperative complications and repeated surgery does not tend to decrease, it is advisable to examine patients more thoroughly to choose the appropriate surgery. Postoperative medical rehabilitation is also required to improve the psycho-emotional state, prevent early and delayed postoperative complications and increase the quality of life of women. This technology can be successfully used in regenerative medicine.
Number of views: 2601 Download in PDF
Modern Trends in Mental Health Delivery Services Worldwide and in the Russian Federation
European Journal of Medicine, 2013, Vol.(1), № 1, p. 22-36.
Number of views: 2744 Download in PDF
5. Yurii A. Kucheryavyi, Zalina F. Tibilova, Dmitrii N. Andreev, Andrei V. Smirnov, Igor' V. MaevEuropean Journal of Medicine, 2013, Vol.(1), № 1, p. 22-36.
Abstract:
This article presents the analysis of the large-scale reform in psychiatric care systems in developed countries that is underway since the second half of the 20th century till now, its positive results and some negative consequences, important for the further development of Russian psychiatric care. The authors focus on two trends in the development of psychiatric care abroad, specifically, integration of psychiatry into general medicine and public-oriented psychiatry development. The use of publications from the mentioned countries on both specific (cited as examples) and global issues, enables to consider general trends and changes in major branches of psychiatric care. Using this data, the authors evaluate the deinstitutionalization (hospital admission decrease) stage and the most topical issues in current Russian psychiatric care, as well as directions for its further development.
This article presents the analysis of the large-scale reform in psychiatric care systems in developed countries that is underway since the second half of the 20th century till now, its positive results and some negative consequences, important for the further development of Russian psychiatric care. The authors focus on two trends in the development of psychiatric care abroad, specifically, integration of psychiatry into general medicine and public-oriented psychiatry development. The use of publications from the mentioned countries on both specific (cited as examples) and global issues, enables to consider general trends and changes in major branches of psychiatric care. Using this data, the authors evaluate the deinstitutionalization (hospital admission decrease) stage and the most topical issues in current Russian psychiatric care, as well as directions for its further development.
Number of views: 2744 Download in PDF
The Role of SPINK1 Gene Mutation in Chronic Pancreatitis Development and Progression
European Journal of Medicine, 2013, Vol.(1), № 1, p. 37-47.
Number of views: 2657 Download in PDF
6. Vladimir N. TitovEuropean Journal of Medicine, 2013, Vol.(1), № 1, p. 37-47.
Abstract:
The research is aimed at the evaluation of the role of SPINK1 gene mutations in the development of different etiologic variants of chronic pacreatitis (CP). The examination of 240 CP patients and 107 healthy people, constituting the control group (CG) was undertaken. All the patients underwent general and biochemical blood analysis, clinical urinalysis, standard coprological examination, immunoenzyme method of fecal elastase-1 determination, esophagogastroduodenoscopy (EGC), ultrasound investigation and/or computer tomography (CT) of abdominal cavity organs and genetic research on mutation N34S (AAT>AGT) identification in SPINK1 gene, using the method of restriction analysis. N34S mutation was determined in 22 (9.2 %) CP patients and in 3 (2.8 %) CG people. The upper frequency of N34S mutation was determined in patients with toxic and idiopathic CP, which has reached 16.7 % in total and 13.3 % for homozygotes. High frequency of N34S mutation was registered in patients with complicated forms of idiopathic CP, which can increase the risk of disease complication.
The research is aimed at the evaluation of the role of SPINK1 gene mutations in the development of different etiologic variants of chronic pacreatitis (CP). The examination of 240 CP patients and 107 healthy people, constituting the control group (CG) was undertaken. All the patients underwent general and biochemical blood analysis, clinical urinalysis, standard coprological examination, immunoenzyme method of fecal elastase-1 determination, esophagogastroduodenoscopy (EGC), ultrasound investigation and/or computer tomography (CT) of abdominal cavity organs and genetic research on mutation N34S (AAT>AGT) identification in SPINK1 gene, using the method of restriction analysis. N34S mutation was determined in 22 (9.2 %) CP patients and in 3 (2.8 %) CG people. The upper frequency of N34S mutation was determined in patients with toxic and idiopathic CP, which has reached 16.7 % in total and 13.3 % for homozygotes. High frequency of N34S mutation was registered in patients with complicated forms of idiopathic CP, which can increase the risk of disease complication.
Number of views: 2657 Download in PDF
Phylogenetically Theory of General Pathology. Nutritive Disturbance Is the Basis of Metabolic Syndrome Pathogenesis, Overeating Syndrome. Leptin and Adiponectin Role
European Journal of Medicine, 2013, Vol.(1), № 1, p. 48-60.
Number of views: 2773 Download in PDF
7. European Journal of Medicine, 2013, Vol.(1), № 1, p. 48-60.
Abstract:
Metabolic syndrome (overeating) is a phylogenetically-determined sequence of symptoms with the same pathogenesis. There is only one etiological factor, namely, increased consumption of physiologically optimal food. Enterocytes and omentum fat cells are phylogenetically paracrine-regulated cell community that realizes the biological reactions of exo- and endotrophy. Visceral obesity, high level of unesterified fatty acids (FA), formation of a pool of micellar FA in the blood, integration of these FA into endothelial cell plasma membrane and enlargement of adipocytes are the causes of hydrodynamic hypertension. Toll-like receptors recognize the albumin associates with greater amount of FA than physiologically required as “non-self” and initiate inflammatory process. “Endoplasm stress” forms in lipid-laden cells, protein synthesis (folding) impairs and induces apoptosis-like cell death. Visceral fat is a phylogenetically repository of FA to fulfill the biological function of homeostasis, trophology, endoecology and adaptation; it is regulated at the early level of paracrine communities and is anatomically limited. The subcutaneous fat repository fulfills the phylogenetically late function of locomotion; the repository size is not anatomically limited. Visceral fat cells don’t have receptors for phylogenetically late insulin (INS); specialized adipoсytes laden with INS and GLUT4 receptors are cells that form the subcutaneous repository. These cells are regulated by phylogenetically late humoral factors at the body level. Leptin is the initiator of humoral hypothalamic regulation of in vivo sized ontogenetically programmed number of visceral INS-insensitive fat cells. It prevents “endoplasm stress” and apoptosis, being designed to regulate the amount of consumed food. Leptin initiates transformation of FA storing from visceral repository into subcutaneous repository. Adiponectin is phylogenetically late humoral hypothalamic regulatory factor that controls optimal number of fat cells in vivo. Its biological role is to regulate the number (proliferation) of insulin-dependent adipocytes in subcutaneous fatty tissue.
Metabolic syndrome (overeating) is a phylogenetically-determined sequence of symptoms with the same pathogenesis. There is only one etiological factor, namely, increased consumption of physiologically optimal food. Enterocytes and omentum fat cells are phylogenetically paracrine-regulated cell community that realizes the biological reactions of exo- and endotrophy. Visceral obesity, high level of unesterified fatty acids (FA), formation of a pool of micellar FA in the blood, integration of these FA into endothelial cell plasma membrane and enlargement of adipocytes are the causes of hydrodynamic hypertension. Toll-like receptors recognize the albumin associates with greater amount of FA than physiologically required as “non-self” and initiate inflammatory process. “Endoplasm stress” forms in lipid-laden cells, protein synthesis (folding) impairs and induces apoptosis-like cell death. Visceral fat is a phylogenetically repository of FA to fulfill the biological function of homeostasis, trophology, endoecology and adaptation; it is regulated at the early level of paracrine communities and is anatomically limited. The subcutaneous fat repository fulfills the phylogenetically late function of locomotion; the repository size is not anatomically limited. Visceral fat cells don’t have receptors for phylogenetically late insulin (INS); specialized adipoсytes laden with INS and GLUT4 receptors are cells that form the subcutaneous repository. These cells are regulated by phylogenetically late humoral factors at the body level. Leptin is the initiator of humoral hypothalamic regulation of in vivo sized ontogenetically programmed number of visceral INS-insensitive fat cells. It prevents “endoplasm stress” and apoptosis, being designed to regulate the amount of consumed food. Leptin initiates transformation of FA storing from visceral repository into subcutaneous repository. Adiponectin is phylogenetically late humoral hypothalamic regulatory factor that controls optimal number of fat cells in vivo. Its biological role is to regulate the number (proliferation) of insulin-dependent adipocytes in subcutaneous fatty tissue.
Number of views: 2773 Download in PDF